Collagen I fiber density increases in lymph node positive breast cancers: pilot study
نویسندگان
چکیده
منابع مشابه
Collagen I fiber density increases in lymph node positive breast cancers: pilot study.
Collagen I (Col1) fibers are a major structural component in the extracellular matrix of human breast cancers. In a preliminary pilot study, we explored the link between Col1 fiber density in primary human breast cancers and the occurrence of lymph node metastasis. Col1 fibers were detected by second harmonic generation (SHG) microscopy in primary human breast cancers from patients presenting w...
متن کاملThe Prognostic Significance of the Lymph Node Ratio in Axillary Lymph Node Positive Breast Cancer
PURPOSE This study evaluated the prognostic impact of the lymph node ratio (LNR; i.e., the ratio of positive to dissected lymph nodes) on recurrence and survival in breast cancer patients with positive axillary lymph nodes (LNs). METHODS The study cohort was comprised of 330 breast cancer patients with positive axillary nodes who received postoperative radiotherapy between 1987 and 2004. Ten-...
متن کاملLevels of specific glycans significantly distinguish lymph node-positive from lymph node-negative breast cancer patients.
One of the most urgent requirements in breast cancer is the development of a blood-based test for early detection and prognosis. Previously published results found a significant difference between specific glycan levels in patients with advanced breast cancer and healthy controls. The aim of this investigation was to address a more clinically relevant problem, i.e., whether the measurement of s...
متن کاملComparison of clinicopathological characteristics of lymph node positive and lymph node negative breast cancer
OBJECTIVE To record various clinicopathological characteristics of breast cancer (BC) in our population and to find an association between these characteristics and axillary nodal metastasis. METHODS This cross-sectional study included 150 BC patients from two tertiary care centers in Karachi from 15(th) February, 2013 to 31(st) March, 2015. Frequencies, percentages, and odds ratio were estim...
متن کاملIncreased Lymph Node Yield in Colorectal Cancer Is Not Necessarily Associated with a Greater Number of Lymph Node Positive Cancers
The presence of lymph node metastasis is a key prognostic factor in colorectal cancer and lymph node yield is an important parameter in assessing the quality of histopathology reporting of colorectal cancer excision specimens. This study assesses the trend in lymph node evaluation over time in a single institution and the relationship with the identification of lymph node positive tumours. It c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2012
ISSN: 1083-3668
DOI: 10.1117/1.jbo.17.11.116017